Chemical Name:
Glutaraldehyde (Glutaral)
CAS Number:
111-30-8
Common Product Code:
G0068
Molecular Formula:
C5H8O2
· Molecular Weight:
100.12 g/mol.
· Common Synonyms:
Pentanedial, Glutaral
Uses:
Glutaraldehyde is a highly effective broad-spectrum biocide and crosslinking agent. The 50% aqueous solution is a concentrated form used as a starting material for various applications.
· Disinfection & Sterilization: A high-level disinfectant for medical equipment (e.g., endoscopes) effective against bacteria, viruses, fungi, and bacterial spores.
· Tissue Fixation: A primary fixative for biological specimens in histology and electron microscopy, preserving cellular structure by crosslinking proteins.
· Industrial Crosslinker: Used in the production of resins, plastics, adhesives, and to modify biomaterials and leather.
Origin
It is a synthetic organic compound. The commercial 50% solution is produced by dissolving glutaraldehyde in water, sometimes with stabilizers (e.g., up to 10% methanol) to prevent polymerization.
What does Glutaraldehyde do in a formulation?
- Antimicrobial Agent / Biocide: Primary function for disinfection and sterilization.
- Crosslinking Agent: Reacts with amine groups to create covalent bonds, hardening or insolubilizing materials like proteins and polymers.
- Fixative: Preserves biological structures for microscopic analysis
Safety Profile:
· Hazard Classification: Danger. Extremely hazardous; fatal if inhaled, toxic if swallowed, causes severe skin burns and eye damage, and can cause organ damage.
· Irritation & Sensitization: A severe skin, eye, and respiratory irritant. Can cause allergic skin reactions and asthma symptoms.
· Key Considerations:
· NEVER use without proper PPE (gloves, eye protection, respiratory protection) and only in well-ventilated areas or fume hoods.
· Environmental Hazard: Very toxic to aquatic life with long-lasting effects.
· Storage: Store in a cool, dark place (<15°C is recommended), under inert gas, and tightly sealed.
Technical profile:
| Property | Values |
| Appearance | Clear, colorless to pale yellow liquid |
| Odor | Sharp, pungent, characteristic odor |
| Active Content | Typically 48.0 - 52.0% w/w |
| pH | 3.0 - 6.0 |
| Density | Approximately 1.06 - 1.13 g/cm³ |
| Boiling Point | >100 °C |
| Melting Point | -14°C to -6°C |
| Solubility | Completely miscible with water and alcohol |
| Storage Temperature | Room temperature (cool, dark place recommended). Some grades require refrigeration |
| Packaging | Available from 10 mL ampoules to 500 mL bottles |