EDTA 4 NA

CAS Number:

13235-36-4

Chemical / INCI Name:

Ethylenediaminetetraacetic acid, tetrasodium salt, tetrahydrate.

Molecular Formula:

C10H12N2O8· 4Na · 4H2O

Molecular Weight:

452.23 g/mol (approximate for the tetrahydrate form)

Common Form:

White crystalline powder

 

Uses:

Tetrasodium EDTA is a powerful chelating agent. It works by binding and sequestering di- and trivalent metal ions in solutions, preventing them from causing issues like precipitation, discoloration, or reduced efficacy of other components

Primary Applications:

· Cosmetics and Personal Care: To control water hardness (removing calcium and magnesium ions) and prevent rancidity, thereby extending product shelf life.

· Chemical Industries and Synthesis: Used as a reaction auxiliary and as a metal complexing agent in catalytic processes.

· Water Treatment: To remove or deactivate heavy metal ions (like lead and iron) that may cause contamination or affect processes.

· Laboratories and Research: Widely used in analytical chemistry and molecular biology (as an inhibitor for metal-dependent enzymes, a component in buffer solutions).

What does Tetrasodium EDTA Tetrahydrate  do in a formulation?

  • Primary Chelating Agent: Its core function. It strongly binds to metal ions such as calcium (Ca²?), magnesium (Mg²?), and iron (Fe³?) to form stable, water-soluble complexes
  • Stabilizer: Prevents oxidative degradation (rancidity) in fat- or oil-containing products by deactivating metal ions that catalyze reactions.
  • Potentiator: Enhances the performance of preservatives and cleaning agents by preventing metals from weakening them.
  • Water Softening Agent: Removes metal ions that cause hardness, improving the foaming and efficiency of detergents and shampoos

 

Safety Profile:

· Hazard Classification: Irritant. Can cause irritation to the skin, eyes, and respiratory tract.

· Skin/Eye Exposure: May cause irritation. Immediate flushing of the eyes with plenty of water is advised, and medical attention should be sought if irritation persists. In case of skin contact, wash the area with water and soap.

· Inhalation Exposure: May irritate the respiratory tract. Move the person to fresh air.

· Required PPE: Protective gloves, safety glasses, and protective clothing are recommended to avoid prolonged or repeated contact.

· Storage: Store in a tightly closed container in a dry, cool, and well-ventilated place. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Technical profile:

PropertyValues
AppearanceWhite crystalline powder
Ph(1% solution)10.8 - 11.1 (alkaline solution)
Solubility in WaterFreely and highly soluble
Typical Purity≥ 99% (by titration)
Storage ConditionsBetween 10-30°C. The substance is hygroscopic (absorbs moisture), so the container must be tightly closed after use