Span 80

CAS Number:

1338-43-8

Chemical Formula:

C24H44O6

EINECS/ELINCS No:

215-665-4

Description:

Span 80,known chemically as Sorbitan Monooleate, is a non-ionic, low-HLB surfactant primarily used as a water-in-oil (W/O) emulsifier, stabilizer, and dispersing agent across multiple industries.

Uses:

t is a versatile surfactant used to create and stabilize emulsions where water is dispersed in oil (W/O), and as a co-emulsifier or dispersant.

· Cosmetics & Personal Care: Used in creams, lotions, facial cleansers, sun protection, makeup (eye, face, lip color), lip care, and bath products as a W/O emulsifier and stabilizer.

· Food Industry: Approved as a food additive (E494), used in items like ice cream and salad dressings to improve texture and stability.

· Pharmaceuticals: Serves as an excipient, wetting agent, and dispersant in lipophilic bases, and is researched for use in drug delivery systems like vesicles and lipid nanoparticles.

· Industrial Applications: Used as a pigment dispersant in non-polar liquids for coatings, paints, adhesives, and textiles.

Origin:

Span 80 is a semi-synthetic, non-ionic surfactant. It is produced by the esterification of sorbitan (derived from sorbitol, a sugar alcohol) with oleic acid, a fatty acid commonly sourced from vegetable oils.

What does SPAN 80 do in a formulation?

Its primary functions are:

• Surfactant - Emulsifying (especially for W/O emulsions)
• Stabilizer
• Dispersing Agent

HAZARDS IDENTIFICATION

Classification:

• Health hazards: None
• Environmental hazards: None
• Physical Hazards: None

Label Elements: None

Signal Word(S): None

Hazard Statements: None

Precautionary Statement: Keep away from heat and fire.

Storage: Stored in a cool, dry and ventilated dry place. Keep container tightly closed

COMPOSITION/INFORMATION ON INGREDIENTS

FIRST AID MEASURES

• Eye Contact: Immediately flush eyes with water for at least 15 minutes while holding eyelids open. If irritation persists get medical attention.
• Skin Contact: In case of contact, immediately remove contaminated clothing, and wash with plenty of water. Get medical attention if irritation persists. Clean contaminated clothing and shoes before reuse
• Inhalation: Inhalation is not an expected route of exposure. If respiratory irritation or distress occurs remove victim to fresh air. Seek medical attention if respiratory irritation or distress continues
• Ingestion: Oral toxicity is low. If ingesting, get medical attention
• Comments: Treat according to person’s condition and specifics of exposure. Skin contact may aggravate existing skin disease.
• Note to Physicians: Treat symptomatically

FIRE-FIGHTING MEASURES

• Extinguishing Media: Use water, carbon dioxide, foam, dry powder
• Fire & Explosion Hazards: May ignite by sparks, heat flames. Carbon dioxide and carbon dioxide may be released by
  fire.
• Special Fire-fighting Protective Equipments: Firefighters should wear NIOSH/MSHA approved self-contained breathing apparatus and full protective clothing

ACCIDENTAL RELEASE MEASURES

• Personal Precautions: Avoid eyes/face contact. Avoid skin contact. Do not take internally
• Environmental Precautions: Do not allow to penetrate into soil, water bodies or drains
• Methods for Cleaning Up: Contain spillage, and then collect with non-combustible absorbent materials, (e.g. sand, dry lime, soda ash) and place in container for disposal according to local/ national regulations. It can also be diluted with a large amount of water before release into the waste water system. For large spill, use dike to contain and then collect, transfer, recycle or discard after treatment

HANDLING AND STORAGE

• Handling Precautions: Avoid contact with skin and eyes. Wash thoroughly after handling. As all chemicals, good industrial hygiene practices should be followed when handling this material
• Storage Conditions: Keep containers tightly closed in a dry, cool and well -ventilated place. Keep away from kindling material, heat source and direct sun light，Do not store close to strong oxidizing agents which could aggravate any fire situation.

EXPOSURE CONTROLS/PERSONAL PROTECTION

• Engineering Measures: Provide adequate ventilation
• Eye Protection: Safety goggles recommended
• Skin Protection: Protective overalls and safety shoes/boots recommended
• Hand Protection: Impervious gloves recommended
• Respiratory Protection: Not required
• Others: Eyewash and safety shower easily accessible to the work area.

PHYSICAL AND CHEMICAL PROPERTIES

• Appearance: Pale yellow Viscous liquid
• Color: Pale yellow
• Odor: A slight odor
• Melting Point: Unknow
• pH(25℃)(1%soln.): Unknow
• Boiling Point: Unknow
• Flash Point: ＞120°C （Closed cup）
• Vapor pressure: Unknow

STABILITY AND REACTIVITY

• Stability: Stable under normal conditions
• Incompatible Materials: Avoid strong oxidizing agents and acids
• Conditions to Avoid: Heat, open flame, spark
• Hazardous Polymerization: Hazardous polymerization will not occur

TOXICOLOGICAL INFORMATION

• Carcinogenicity: Not considered to be a carcinogen according the animal tests
• Teratogenicity: Not available
• Mutagenicity: Testing has shown this product to be non-mutagenic when make the rats expose in 100mg/ml products for 24h

ECOLOGICAL INFORMATION

• Ecological Toxicity: None Established
• Persistence and Degradability: It is biodegradable in the environment
• Mobility: The product will dissolve in water

DISPOSAL CONSIDERATIONS

• Product Disposal: Dispose of in accordance with local regulations
• Packaging Disposal: Any containers or equipment used should be decontaminated immediately after use

TRANSPORT INFORMATION

• Road and Rail Transport: Not subject to ADR/RID code
• Sea Transport (IMDG): Not subject to IMDG code
• Air Transport (ICAO/IATA): Not subject to ICAO/IATA regulations

REGULATORY INFORMATION

Applicable Laws: Provisions of the Regulations for the Safe Handling of Chemicals in the Workplace, particularly those relating to the safe use, production, storage and transportation of dangerous chemicals

Chemical Inventories:

• AICS: All ingredients listed or exempt.
• DSL: All chemical substances in this material are included on or exempted from the DSL.
• IECSC: All ingredients listed or exempt.
• MITI: All components are listed on ENCS or its exempt rule.
• KECL: All ingredients listed, exempt or notified
• EINECS: All ingredients listed or exempt
• PICCS: All ingredients listed or exempt
• TSCA: All chemical substances in this material are included on or exempted from listing on the TSCA Inventory of Chemical Substances

Technical Specification

The data is just for reference only based on elemntra lab testing

Packaging:

200kg/drum

Storage and Preservation:

Preserved dry at room temperature, avoid sunlight.

Shelf Life:

2 years