Magnesium Ascorbyl Phosphate

CAS Number:

113170-55-1

Chemical / IUPAC Name:

Magnesium bis[(2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate] phosphate

INCI Name:

Magnesium Ascorbyl Phosphate

Molecular Formula:

 C12H14MgO18P2 (anhydrous) or hydrated forms

Molecular Weight:

540.47 g/mol (anhydrous)

Other Names:

MAP, Vitamin C Phosphate, Magnesium L-Ascorbyl-2-Phosphate, VC-PMG

Uses:

Magnesium Ascorbyl Phosphate (MAP) is a stable, water-soluble derivative of Vitamin C (L-Ascorbic Acid) . It is designed to overcome the stability issues of pure Vitamin C (which oxidizes rapidly) while retaining its powerful antioxidant and skin-benefiting properties .

· Skin Care & Cosmetics: Widely used in anti-aging serums, moisturizers, creams, lotions, and sunscreens for its multiple skin benefits .

· Key Benefits:

  · Antioxidant Protection: Neutralizes free radicals caused by UV exposure and pollution, preventing premature skin aging .

  · Collagen Synthesis: Stimulates collagen production, improving skin firmness and reducing fine lines and wrinkles .

  · Skin Brightening: Inhibits melanin production, helping to fade dark spots, hyperpigmentation, and even skin tone .

  · Photoprotection: Provides some protection against UV-induced damage (works synergistically with sunscreens) .

Origin

Magnesium Ascorbyl Phosphate is a semi-synthetic compound produced by chemically modifying L-Ascorbic Acid (Vitamin C) derived from natural sources like corn or rice. The modification involves phosphorylation and salt formation with magnesium .

What does Magnesium Ascorbyl Phosphate do in a formulation?

• Antioxidant: Protects skin from environmental oxidative stress .
• Collagen Production Stimulator: Promotes collagen synthesis for anti-aging benefits .
• Skin Lightening Agent: Reduces melanin formation, fading hyperpigmentation .
• Skin Conditioning Agent: Improves overall skin texture and hydration .

Safety Profile:

· General Hazard Classification: Considered safe for topical use in cosmetics at recommended concentrations .

· Concentration Limits: Typically used at 1 - 5% in cosmetic formulations. Higher concentrations (up to 10-15%) can be used in specialized products .

· Irritation & Sensitization: Generally regarded as non-irritating and non-sensitizing at typical use concentrations. It is much gentler than L-Ascorbic Acid (pure Vitamin C), making it suitable for sensitive skin .

· Stability: Excellent stability compared to pure Vitamin C. MAP is resistant to oxidation and does not degrade rapidly when exposed to air, light, or water. Formulations maintain potency longer .

· pH Compatibility: Stable and effective at a wider pH range (pH 6.0 - 7.5) compared to L-Ascorbic Acid (which requires low pH) .

· Penetration: Effectively penetrates the skin and converts to active Vitamin C within skin cells .

· Regulatory Status: Approved for use in cosmetics worldwide .

Technical profile: