CAS Number:
110-27-0
Chemical / IUPAC Name:
Propan-2-yl tetradecanoate
INCI Name:
Isopropyl Myristate
Molecular Formula:
C17H34O2
Molecular Weight:
270.45 g/mol
Uses:
Isopropyl Myristate is a clear, low-viscosity, oily liquid that is a common emollient and solvent in personal care products. It is valued for its light, non-greasy skin feel.
· Cosmetics & Personal Care: A key ingredient in lotions, creams, moisturizers, hair conditioners, and sunscreens for its skin-softening properties. It is present in nearly 4% of cosmetics, commonly in dry shampoos, hair dyes, and deodorant sprays.
· Pharmaceuticals: Used in topical preparations as a penetration enhancer to help active ingredients absorb through the skin.
· Fragrances & Perfumery: Acts as a solvent and diluent for perfume oils and as a base for products like linen sprays.
· Other Uses: Found in treatments for head lice, pet flea/tick products, and two-phase mouthwashes.
Origin:
It is the ester formed from isopropyl alcohol and myristic acid. Industrially, it is synthesized via the esterification of these two components. Myristic acid can be derived from vegetable sources like coconut oil.
What does Isopropyl Myristate do in a formulation?
According to INCI (International Nomenclature of Cosmetic Ingredients), its main functions are:
- Emollient: Softens and smooths the skin.
- Solvent and Perfuming Agent: Dissolves and carries fragrance materials.
- Masking Agent: Reduces or masks undesirable base odors.
Binding Agent: Helps ensure cohesion of different ingredients.
Safety Profile:
· General Hazard Classification: Considered to have low acute toxicity. It is not classified as hazardous for transport and is generally safe for topical use in cosmetics.
· Primary Hazards: It is a combustible liquid. Classified as an irritant (H315) that may cause skin irritation.
· Important Safety Note: Isopropyl myristate is frequently classified as comedogenic, meaning it can clog pores and potentially worsen acne, especially when used in high concentrations.
Technical profile:
| Property | Values |
| Appearance | Colorless to pale yellow, clear liquid |
| Odor | Faint, characteristic, or practically odorless |
| Purity / Assay | Often ≥98% or 99% min |
| Boiling Point | 167°C at 9 mmHg or 192-194°C at 20 mmHg. These are equivalent measurements at different pressures |
| Melting / Freezing Point | Approx. 3°C to -3°C |
| Density | 0.85 g/cm³ at 20-25°C |
| Flash Point | 152-164°C (306-327°F) - Closed cup |
| Solubility | Immiscible with water. Miscible with alcohols, oils, and most organic solvents. |
| Viscosity | 4.8 cP at 25°C |
| Refractive Index | 1.433 - 1.438 at 20°C |