EDTA 4 NA

CAS Number:

13235-36-4

Chemical / INCI Name:

Ethylenediaminetetraacetic acid, tetrasodium salt, tetrahydrate.

Molecular Formula:

C10H12N2O8· 4Na · 4H2O

Molecular Weight:

452.23 g/mol (approximate for the tetrahydrate form)

Common Form:

White crystalline powder

Uses:

Tetrasodium EDTA is a powerful chelating agent. It works by binding and sequestering di- and trivalent metal ions in solutions, preventing them from causing issues like precipitation, discoloration, or reduced efficacy of other components

Primary Applications:

· Cosmetics and Personal Care: To control water hardness (removing calcium and magnesium ions) and prevent rancidity, thereby extending product shelf life.

· Chemical Industries and Synthesis: Used as a reaction auxiliary and as a metal complexing agent in catalytic processes.

· Water Treatment: To remove or deactivate heavy metal ions (like lead and iron) that may cause contamination or affect processes.

· Laboratories and Research: Widely used in analytical chemistry and molecular biology (as an inhibitor for metal-dependent enzymes, a component in buffer solutions).

What does Tetrasodium EDTA Tetrahydrate  do in a formulation?

• Primary Chelating Agent: Its core function. It strongly binds to metal ions such as calcium (Ca²?), magnesium (Mg²?), and iron (Fe³?) to form stable, water-soluble complexes
• Stabilizer: Prevents oxidative degradation (rancidity) in fat- or oil-containing products by deactivating metal ions that catalyze reactions.
• Potentiator: Enhances the performance of preservatives and cleaning agents by preventing metals from weakening them.
• Water Softening Agent: Removes metal ions that cause hardness, improving the foaming and efficiency of detergents and shampoos

HAZARDS IDENTIFICATION

•  Classification:

 Skin Irritation: 2

 Eye Damage: 1 

Aquatic Acute: 2 

Aquatic Chronic: 3 

• Signal Word(S): Warning 
• Hazard Statements: Causes skin irritation. Causes serious eye damage. Harmful to aquatic life with long lasting effects. 
• Precautionary Statement: Wash thoroughly after handling. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. 
• Storage: Stored in a cool ventilated dry place

COMPOSITION/INFORMATION ON INGREDIENTS

FIRST AID MEASURES

•  Eye Contact: Immediately flush eyes with water for at least 15 minutes while holding eyelids open. If irritation persists get medical attention. 
•  Skin Contact: In case of contact, immediately remove contaminated clothing, and wash with plenty of water. Get medical attention if irritation persists. Clean contaminated clothing and shoes before reuse.
•   Inhalation: Inhalation is not an expected route of exposure. If respiratory irritation or distress occurs remove victim to fresh air. Seek medical attention if respiratory irritation or distress continues.
•   Ingestion: Oral toxicity is low. If ingesting, get medical attention. 
•  Comments: Treat according to person’s condition and specifics of exposure. Skin contact may aggravate existing skin disease. 
•  Note to Physicians: Treat symptomatically.

FIRE-FIGHTING MEASURES

•  Extinguishing Media: Recommended (small fires): dry chemical, carbon dioxide, Recommended (large fire): alcohol foam, universal foam, water spray, Not recommended: water jet (frothing possible). 
•  Fire & Explosion Hazards: Product will burn under fire conditions. Closed containers may explode (due to the build-up of pressure) when exposed to extreme heat. 
•  Special Fire-fighting Protective Equipments: Firefighters should wear NIOSH/MSHA approved self-contained breathing apparatus and full protective clothing. 
•  Combustion Products: Oxides of nitrogen, oxides of sulfur, oxides of carbon

ACCIDENTAL RELEASE MEASURES

• Personal Precautions: Avoid eyes/face contact. Avoid skin contact. Do not take internally. 
•  Environmental Precautions: Do not allow to penetrate into soil, water bodies or drains. 
•  Methods For Cleaning Up: Small Spills: Use a non-combustible material like vermiculite, sand or earth to soak up the product and place into a container for later disposal. Large Spills: Dike far ahead of liquid spill for later disposal.

HANDLING AND STORAGE

• Handling Precautions: Avoid contact with skin and eyes. Wash thoroughly after handling. As all chemicals, good industrial hygiene practices should be followed when handling this material.
•  Storage Conditions: Store in plastic, plastic lined or stainless steel, tightly closed containers at 15~40℃，Do not store close to strong oxidizing agents which could aggravate any fire situation.

EXPOSURE CONTROLS/PERSONAL PROTECTION

•  Engineering Measures: Provide adequate ventilation.
•  Eye Protection: Safety goggles recommended.
•  Skin Protection: Protective overalls and safety shoes/boots recommended. 
•  Hand Protection: Impervious gloves recommended.
•   Respiratory Protection: Not required. 
•  Others: Eyewash and safety shower easily accessible to the work area

PHYSICAL AND CHEMICAL PROPERTIES

•  Appearance: Powder 
•  Color (APHA): White 
•  Active Content, %: 99.0 Min 
•  Melting Point,°C : > 150
•   pH: No data available 
•  Boiling point : No data available 
•  Flammability (solid, gas) : Non flammable
•   Explosive properties : Not explosive

STABILITY AND REACTIVITY

•  Stability: Stable under normal conditions.
•  Incompatible Materials: Avoid strong oxidizing agents and acids. 
•  Conditions to Avoid: Heat, open flame, spark. 
•  Hazardous Polymerization: Hazardous polymerization will not occur

TOXICOLOGICAL INFORMATION

•  Carcinogenicity: Not considered to be a carcinogen according the animal tests. 
•  Teratogenicity: Not available
•  Mutagenicity: Testing has shown this product to be non-mutagenic when make the rats expose in 100mg/ml products for 24h.

ECOLOGICAL INFORMATION

•  Ecological Toxicity: None Established.
•  Persistence and Degradability: It is biodegradable in the environment. 
•  Mobility: The product will dissolve in water

DISPOSAL CONSIDERATIONS

•  Product Disposal: Dispose of in accordance with local regulations. 
•  Packaging Disposal: Any containers or equipment used should be decontaminated immediately after use.

TRANSPORT INFORMATION

• Road and Rail Transport: Not subject to ADR/RID code. 
•  Sea Transport (IMDG): Not subject to IMDG code. 
•  Air Transport (ICAO/IATA): Not subject to ICAO/IATA regulations

REGULATORY INFORMATION

• Applicable Laws: Provisions of the Regulations for the Safe Handling of Chemicals in the Workplace, particularly those relating to the safe use, production, storage and transportation of dangerous chemicals. 
• Chemical Inventories: 

AICS: All ingredients listed or exempt.

 DSL: All chemical substances in this material are included on or exempted from the DSL. 

IECSC: All ingredients listed or exempt. 

MITI: All components are listed on ENCS or its exempt rule.

 KECL: All ingredients listed, exempt or notified. 

EINECS: All ingredients listed or exempt. 

PICCS: All ingredients listed or exempt. 

TSCA: All chemical substances in this material are included on or exempted from listing on the TSCA Inventory of Chemical Substances.

Application Method

EDTA 4Na is applied in detergent, dyeing auxiliary, fiber treatment agent, cosmetic additive, food additive and agricultural micro-fertilizer, as well as in mariculture

Handling and storage conditions

Avoid inhalation and ingestion. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Shelf life

2 years from the date of production with sealing tightly.

Packaging

25kg bag.

 20’FCL=20MT, without pallets

20’FCL=18MT, with pallets