CAS Number:
111-46-6 (Note: CAS 67-63-0 listed in some searches belongs to Isopropyl Alcohol)
INCI/Chemical Name:
Diethylene Glycol
Molecular Formula:
C4H10O3
Molecular Weight:
106.12 g/mol
Uses:
DEG is primarily an industrial chemical with a wide range of applications .
· Chemical Production: Used in manufacturing unsaturated polyester resins, polyurethanes, and plasticizers.
· Solvent: Serves as a solvent for nitrocellulose, resins, dyes, oils, and in applications like printing inks and textile processing .
· Specialty Applications: Functions as a humectant (moisturizer) for products like tobacco and glue, and as a dehydrating agent for natural gas . It is also a component in brake fluids, lubricants, and antifreeze formulations .
Important Note on Personal Care Use: Pure Diethylene Glycol is not a common ingredient in modern cosmetics due to its toxicity. A chemically related compound, Diethylene Glycol Monoethyl Ether (INCI: Ethoxydiglycol), is used as a solvent and penetration enhancer but is subject to restrictions in the EU and UK .
Origin:
DEG is a synthetic compound. It is produced industrially as a co-product during the manufacture of ethylene glycol (MEG), via the partial hydrolysis of ethylene oxide .
What does Diethylene Glycol do in a formulation?
In formulations where it is used, its primary technical functions include acting as a solvent, humectant, and viscosity-controlling agent
Safety Profile:
· Toxicity: DEG is toxic to humans and can cause kidney failure, metabolic acidosis, and death if ingested, even in relatively small amounts . It has been responsible for multiple fatal poisoning epidemics historically when mistakenly used in medicines and consumables .
· Regulatory Status: Its use is severely restricted in food, drugs, and cosmetics. Regulations typically allow only trace amounts (e.g., <0.2%) as an impurity in other ingredients like polyethylene glycol . It is not an ingredient for routine cosmetic formulation.
· Hazards: It is combustible and can be a mild skin and eye irritant.
Technical profile:
| Property | Values |
| Appearance | Colorless, odorless, viscous oily liquid |
| pH | ~5.5-7.0 (50 mg/mL in water) |
| Boiling Point | 244 - 245 °C |
| Melting Point | -10.45 °C |
| Density | 1.118 g/mL at 25°C |
| Solubility | Miscible with water, alcohol, and ether |
Summary:
Diethylene Glycol (DEG) is an industrial solvent and chemical intermediate with significant human toxicity. Its direct use in personal care is highly uncommon and regulated due to safety risks.